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BIF401 : Bioinformatics I

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Course Info

Course Category

Bioinformatics

Course Level

Undergraduate

Credit Hours

3

Pre-requisites

N/A

Instructor

Saddia Bano
MS Bioinformatics
NUST, Islamabad, Pakistan

Course Contents

Introduction to bioinformatics (history, timeline, databases, sequence storage, retrieval and analysis) Similarity and Homology Creating alignments (local, global alignment, pairwise and multiple sequence alignments) Phylogenetic analysis Dot matrix plots Dynamic programming algorithm (word (k-tuple) methods, substitution matrices PAM and BLOSUM, scoring algorithms, gap penalties) Online tools (BLAST, BLAT and FASTA and PDB file structure)