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BT501 : Health Biotechnology

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Jahanzaib Azhar
Mphil Healthcare Biotechnology
NUST, Islamabad

Course Contents

What is biotechnology all about, Medical products developed by using biotechnology tools Antibiotics, Recombinant insulin, Vaccines, Monoclonal antibodies, Bioengineered Tissues, Adult Stem Cell Therapy, Emerging Trends-Embryonic Stem Cells, Human Genome Project, RNA Interference Technology, Recombinant DNA Technology, Biochips, Gene Therapy, Liposome based drug delivery, BionanoTechnology, Chromosomal Abnormalities, Chromosome Structural Abnormalities, Chromosome Numerical Abnormalities, Sex Chromosome Abnormalities, Single Gene Disorders, Cystic Fibrosis, Fragile X Syndrome, Hemophilia, Huntington diseases, Sickle cell anemia, Tay sachs diseases, Thalassemia, Polygenic disorder Diabetes, Diabetes Mellitus type 1, Type 2 Diabetes, Alzheimer-diseases, Breast cancer, Cardiovascular Disease, Mitochondrial Diseases, Mitochondrial homeostasis, Parkinson Disease, Immunological Approaches To Detect Protein Biomarkers of Disease, ELISA,  Measuring Disease-Associated Proteins by Sandwich ELISA, Diagnosing Autoimmune Diseases by an Indirect ELISA, Immunoassay for infectious diseases, Protein Array to Detect Polygenic Disease, Immunoassay for Protein Conformation-specific Disorder, DNA based approaches to diagnosis diseases, Allele specific Hybridization, Oligonucleotide ligation assay, Padlock probes, Allele Specific PCR, TaqMan PCR,  Real-time PCR for infectious diseases,  DNA Sequencing Technologies, Dideoxynucleotide Procedure, Pyrosequencing, Sequencing Using Reversible Chain Terminators, Sequencing by Ligation, The Immune Response, Functions of the Immune System, Innate immune system, Cellular network of innate immune system, Adaptive immune system, T -cells,  B lymphocytes and antibodies, Passive memory, Active memory and immunization, Immune diseases, Autoimmunity, Classifications of cell transplantation, Allogeneic cells, Organ Transplantation, Transgenic organisms, Production of Transgenic Animals, Transfer of Transgene in the Animal, Pronuclear Microinjection, DNA Transfer Through Virus, Embryonic Stem Cell Mediated Gene Transfer, Sperm-Mediated Transgenesis, Somatic Cell Nuclear Transfer, Medical Applications of Transgenic Animals, Xenotransplantation, Therapeutic proteins, Recombinant human insulin, Recombinant human growth hormone, Recombinant blood clotting factor VIII, Recombinant tissue plasminogen activator, Recombinant erythropoietin, Significance of vaccines, Live attenuated vaccines, Inactivated vaccines, Toxoid vaccines & Component vaccines, DNA Vaccine