Course Info
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Course Category
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Molecular Biology
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Course Level
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Graduate
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Credit Hours
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3
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Pre-requisites
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N/A
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Instructor
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Dr. Asif Nadeem
PhD
UVAS, Lahore-Pakistan
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Course Contents
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Course Objectives:
To acquaint students with principles of biosafety and ethical perspectives pertaining to biotechnology
Overall Course Contents:
Introduction to ethics and bioethics; Current issues in environmental ethics; The ethics of animal research; code of ethics for biologist; Ethics and genetic modification; Biotechnology and risk factors; Applications of biotechnology, ethical issues related to GMOs; Ethics and animal biotechnology; Thoughts on eugenics; Use of Human Genetic Information, Burden of genetic information, Genetic piracy; Ethics of human cloning, Therapeutic cloning; Stem cell debate; Genetic counselling; Introduction to Biosafety - definition, concept, uses and abuses of genetic information, and biohazards; good laboratory practices; Biosafety, Biosecurity, Bioweapons, Biohazard; Lab safety protocols, Sterlization and disinfection, Lab biosaftey level criteria; Safety for support staff, Immunization of staff; WHO biosafety collaborating centers; Biosecurity and bioterrorism, Pakistan biosecurity system; Risk assessment; Occupational Health and Immunoprophylaxis; Biosecurity education for the next generation of life scientists:
Topic wise Course Contants:
Science Ethics and Values, Attitudes to science, what is ethics, The development of ethics, The growth of bioethics, Bioethics in the 21st century, Making ethical decisions, The place of humans in nature, Valuing the Environment, Themes in environmental ethics, Current issues in environmental ethics, Terrestrial and aquatic pollution: environmental ethics, Global climate change: environmental ethics, Environmental degradation and loss of biodiversity: Environmental ethics, The ethics of animal research, Animals in sport, companionship, leisure, and fashion, Animals for food and draughting, Code of ethics for biologists, Patient-physician relationship, Codes for nurses, Patient rights and responsibilities, Truth telling, Informed consent, Patients' advance directives, Management of information, Problems of moral justification, Maternal-fetal relationship and rights, Refusal of treatment, Ethics and genetic modification, Biotechnology and risk factors, Misuse of Biotechnology, Nanobiotechnology, Cybernetics, Applications of biotechnology, Ethical issues of GM food, Risk factors of GM food, Ethics and animal biotechnology, Human genome project, Thoughts on eugenics, Use of Human Genetic Information, Genetic diagnosis, Genetic screening, Genetic discrimination, Burden of genetic information, Fact or fiction, Genes—the wider issues, Gene patents in agriculture, Gene patents in medical genetics, Genetic piracy, Cloning of sheep and frog, Ethics of human cloning, Ethics—early human embryo, Therapeutic cloning, Designer babies, Case study 1, Case study 2, Case study 3, Case study 4, Case study 5, Case study 6, Case study 7, Case study 8, Stem cell debate, Conclusion controversies, Genetic counselling, Responding to trafficking and HIV, Responding to disasters, Biosafety, Biosecurity, Bioweapons, Biohazard, Application forms, Lab safety protocols, Classification of pathogens, Containment, Safe handling of biological spills, Sterilization and disinfection, Biohazards-animal handling, Handling of lab equipment, Report of accidents, Water disposal, Lab biosafety level criteria, Biosafety level 1, Biosafety level 2, Biosafety level 3, Biosafety level 4, Biosafety measures for TB lab, Low risk TB labs, Moderate risk TB labs, High risk TB labs, Safety Equipment, Personal Protective Equipment, Plans for Emergency, Transport of Infectious Material, Recombinant DNA Technology, Hazardous chemicals, Fire Hazard, Electrical Hazards, Noise, Ionizing radiation, Biosafety officer, Biosafety committee, Safety for support staff, Training programs, Safety checklist, First aid, Immunization of staff, WHO biosafety collaborating centers, US biosecurity legislation, US biosecurity regulations, US biosecurity guidance, Canada biosecurity legislation, Japan biosecurity legislation, Other countries biosecurity, Design biosecurity plan, Objectives of lab biosecurity, Biosecurity and bioterrorism, International obligations, Pakistan biosecurity system, Risk assessment, Risk assessment methodology, Evaluate pathogens and toxins, Potential adversaries, Evaluate scenarios, Characterize risk, Risk reduction, Components of biosecurity, Physical security, Physical security elements, Integration with lab biosafety, Personnel security, Personnel security elements, Accountability Elements, Transport Security, Transport Security Elements, Information Security, Information Security Elements, Biosafety Rules for Virology Labs, Fire Extinguishers, Fire Exit, Fire wardens, Fire Assembly Area, National Biosafety Rules, Application of National Biosafety rules, Establishment of National Biosafety Committee, Functions of National Biosafety Committee, Technical Advisory Committee, Institutional Biosafety Committee, Prohibition and License Requirements, Confidential Information, Risk assessment and Risk Management, Decision making and Communication of Decision, Grant of License, Application for re-examination, Import/Export of GMOs, Permission and approval for Food Stuff, Notify Interruptions/Accidents, Pakistan Bio-safety Measures, Implementation of National Laws, Efforts to mitigate Biological threats, Threats of Biological Weapons, High Containment biological Labs, High Containment biological Labs (Part 2), Public participation and Access to information, International framework on Biosafety, Conclusion, Problem 1, Problem 2, Problem 3, Problem 4, Problem 5, Problem 6, Problem 7, Problem 8, Problem 9, Problem 10, Problem 11, Problem 12, Problem 13, Problem 14, Problem 15, Problem 16, Problem 17, Problem 18, Problem 19, Problem 20, Problem 21, Problem 22, Problem 23, Problem 24, Problem 25, Problem 26, Problem 27, Problem 28, Problem 29, Problem 30, Problem 31, Problem 32, Problem 33, Problem 34, Problem 35, Problem 36, Problem 37, Problem 38, Problem 39, Problem 40, Problem 41, Problem 42, Problem 43, Problem 44, Problem 45, Problem 46, Problem 47, Problem 48, Problem 49, Problem 50, Problem 51, Problem 52, Problem 53, Problem 54, Problem 55, Problem 56, Problem 57, Problem 58, Problem 59, Problem 60, Problem 61, Problem 62, Problem 63, Occupational Health and Immunoprophylaxis, Occupational Health Support Service Elements, Occupational Health Support Service Elements 2, Bacillus anthracis, Brucella Species, Campylobacter, Neurotoxin-producing Clostridia species, Corynebacterium diphtheriae, Helicobacter species, Neisseria gonorrhoeae, Salmonella serotypes, Treponema pallidum, Cryptococcus Neoformans, Blood and tissue protozoal parasites, Hepatitis B Virus, Hepatitis C Virus, Human Herpes Virus, Influenza, SARS, Agriculture pathogen biosafety, Foot and Mouth Disease Virus, Newcastle Disease (ND) Virus, Integrated pest management, Class I BSC, Class II BSC, Class III BSC, Hepatitis A Virus, Hepatitis E Virus, Biosafety and biosecurity in hematology lab, Intestinal Protozoal Parasites, Biosafety and biosecurity in Nanotechnology, Biosafety and biosecurity in cybernetics, Biosecurity education for the next generation of life scientists.
Recommended Books:
1. Altman A and Hasegawa PM, 2012. Plant Biotechnology and Agriculture:
Prospects for the 21st Century. 1
st Edition; Academic Press.
2. Laboratory Biosafety Manual, WHO, 2006. 3rd Edition; AITBS Publishers and
Distributors, India. (Available online free of cost).
3. Furr AK, 2000. CRC Handbook of Laboratory Safety. 5th Edition; CRC Press. 4. Jose Maria A, 2003. Genes Technology and Policy. Available online at;
http://www.apdip.net/publications/iespprimers/eprimer-genes.pdf
5. Krishna VS, 2007. Bioethics and Biosafety in Biotechnology. New Age
International Publishers.
6. National Biosafety Guidelines, 2005. Pakistan Environmental protection
Agency
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