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BIO201 : Cell Biology

Course Overview

Course Synopsis

This course will help students to understand the building blocks of life "The cells", how they made up of, cell constituents, cell interaction, cell processes, cell signalling and cells in system biology as a whole. Furthermore, it is best course for understanding molecules and units of life, biocatalysts, cell division/membranes, its origin and genetics in general.

Course Learning Outcomes

Understanding the units of life

  • After taking this course, students will enable themselves to understand the basics of the cell biology cum road map for further advanced courses in the same subject or other related arena of cell/molecular biology, genetics and bioinformatics.
  • Cell origin, Cell evolution, Cell interactions, Cell mobility, Cell processes, Cell membranes, Cell division, Genetics, Cell signalling and Cell behavior

Course Calendar

Introduction to Cell Biology1
Composition of Matter2
Molecules of Life3
Ptoteins: Polymers of Amino Acids4
Protein Structure5
Protein Interaction6
Carbohydrates: Sugar Polymers7
Carbohydrates: Glycosidic linkages8
Lipids: Nonpolar Hydrocarbons9
Lipids: Saturated & Unsaturated10
Nucleic Acids: DNA & RNA11
Assignment 1
Unit of Life13
Journey into the Cell14
Size Matters15
The Nucleus16
The Endoplasmic Reticulum18
Golgi & Lysosomes19
Motor Proteins23
The Miracle Workers24
Free Energy26
Exergonic & Endergonic Reactions27
ATP Hydrolysis28
Enzymes Mechanisms30
Enzyme Helpers31
Enzyme Regulation32
Membrane Components34
Recognition and Adhesion35
Transport across membranes36
Vesicle formation37
Cell division38
Cell Cycle39
Quiz # 1
Genetics introduction47
Mendel Experiment48
Learned lesson-Mendel Experiment49
Mendels first law of segregation50
Mendels second law51
Aberrant Phenomenna52
Linkage and recombination53
Genetics Maps54
Clinical Genetics-I55
Clinical genetics-I (Conti..)56
X linked disorders57
Multifactorial disorders58
Cytogenetic disorders59
Autosomal genetic disorders60
Cytogenetic disorders of sex chromosome61
Search for heredity molecules62
Search for heredity molecules 263
Investigating heredity molecules64
DNA function from structure65
Replication models66
DNA replication the molecular view67
DNA replication the process68
Assignment 2
The Dilemma 169
The Dilemma 2 & 370
PCR technology71
PCR animation72
PCR Conti..73
Detecting amplified DNA74
Gel electrophoresis animation75
PCR technology application76
DNA Fingerprinting77
DNA Sequencing78
Restriction Endonucleases79
Genetic Engineering80
DNA Transfer82
Genetic information is converted into proteins83
Central Dogma of Molecular Biology84
Genetic code86
Charging tRNA87
Translation workbench88
Midterm Exam
Protein targeting90
Transcription regulation92
Transcription regulation in E.Coli93
Transcription Regulation in E.Coli 294
Transcription Regulation in Eukaryotes95
Eukaryotic Transcription96
RNA Processing97
Cell signalling and prehistoric world98
The Instructions and the Design99
The Modes and Principles100
The Modes and Principles II101
The Modes and Principles III102
Signalling in E.Coli103
G protein linked receptor104
Protein Kinases A105
G proteins106
G proteins vision107
Cell signalling and Us108
Cell signaling and memory109
Enzyme linked receptors110
Enzyme linked receptors 2111
Enzyme linked receptors 2 (Conti...)112
RTK signalling gone wrong113
PI3 Kinase114
PKB apoptosis inhibition115
JAK-STAT signaling116
TGF-Beta receptor Family117
Proteolysis Signaling Pathways118
Quiz No 2
Immune system119
Immune system 2120
Immune system 3121
The B-Cells123
The B-Cells 2124
The Antibodies125
Immunological memory126
Acquired Immunological Tolerance127
Antibody diversity128
Class Switching129
T-Cells and TCR130
APCs activate T cells131
Cytotoxic T cells133
Helper T Cells134
TH-1 and TH-2135
TH-2 B-Cell activation136
Checks and Balances137
Complement System138
Complement System 2139
The Alternative Pathway140
Neoplastic Transformation141
Growth promoting oncogenes142
Growth promoting oncogenes Cyclins and CDKs143
Growth promoting oncogenes Cyclins and CDKs (Conti..)144
DNA Repairing genes145
Apoptosis Genes146
Protein Sorting147
Protein Sorting Mechanism148
Nuclear Transport149
Nuclear localization signals [NLSs] and transport150
Nuclear Receptors151
The Ran Cycle152
Control of import and export153
Protein Transport into Mitochondria154
The Translocators155
ER Transport Introduction156
ER Transport157
Multipass Transmembrane Proteins159
Vesicle Transport160
COPI the Retrieval Process162
Lysosomal Transport163
Tissue Replacement165
Organ repair via stem cell166
Customized stem cells167
Adult stem cells168
Cytokines induced stem cell proliferation and differentiation169
In-vitro organ/tissue fabrication170
Rules and cell culturing equipment171
Cell culturing equipment172
Getting started173
Mammalian cell culture174
Culturing Cells175
Sub culturing and cell banking176
Identifying different stages of cell cycle177
Finalterm exam
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