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BT731 : Modern Biotechnology: Principles & Applications

Course Overview

Course Synopsis

This course is designed to develop understanding of the students about the scope of biotechnology, Differentiate between the fine differences between biotechnology and allied fields, Appreciate the commercial potential of biotechnology products, understand the principles of microbial growth and relate them with large scale manufacturing at the industrial scale, Appreciate advances in healthcare biotechnology and understand how it is shaping up modern biopharmaceutical sector, Comprehend how biotechnology is protecting the environment, understand how analytical biotechnology is exploited to make biosensors, how biotechnology products are going to revolutionize clinical trials, what are going to be fuels of the future

Course Learning Outcomes

After completing this course, students will be able to

  • Understand and comprehend the scope of biotechnology
  • Differentiate between the fine differences between biotechnology and allied fields
  • Appreciate the commercial potential of biotechnology products
  • Understand the principles of microbial growth and relate them with large scale manufacturing at the industrial scale
  • Identify and differentiate between various fermentation systems
  • Appreciate advances in healthcare biotechnology and understand how it is shaping up modern biopharmaceutical sector
  • Understand how analytical biotechnology is exploited to make biosensors
  • know about biotechnology products that are going to revolutionize clinical trials


Course Calendar

1 Introduction
2 Biotechnology in 21st Century
3 Roots of Biotechnology
4 Roots of Biotechnology_2
5 Discovery of DNA
6 Dawn of Biotechnology
7 Commercialising Biotechnology
8 Biotechnology Giants
9 PCR & Biotechnology
10 Human Genome Project
11 Human Genome Project_2
12 Emerging Fields
13 Pharmacogenomics
14 Structure of DNA
15 Replication
16 Replication_2
17 Transcription 1
18 Transcription 2
19 Transcription 3
20 Code of Codons
21 Translation 1
22 Translation 2
23 Translation 3
24 Expanding the genetic code
25 Amino Acids
26 Peptide Bond
27 Foreces Defining Protein Structure
28 Forces Defining Protein Structure_2
29 Secondary Structure
30 alpha-helix
31 beeta-sheets
32 Super Secornday and Tertiary
33 Super Secondary & Tertiary_2
34 Engineering the three domains
35 Engineering the three domains_2
36 Learning from extremophiles
37 Learning from extremophiles_2
38 Engineering the Prokaryotes
39 Restriction Endonuclease_1
40 Restriction Endonuclease_2
41 DNA Ligase
42 Vectors in Prokayotes
43 Plasmid Classification
44 Bacterial Plasmids
45 Development of Plasmids
46 Insertional Inactivation
47 Expression vectors
48 Life cycle of Bacteriophage
49 Vectors based on the lambda _1
50 Vectors based on the lambda _2
51 Genome of M13
52 Vectors based on M13
53 Cosmids
54 Making genomic libraries in E.coli
55 Do Bacteria Age
56 Bacterial Growth Curve
57 Measuring Bacterial Growth
58 High Copy number & Expression Strategies_1
59 High Copy number & Expression Strategies_2
60 Protein Secretion Pathway
61 Type 1 Protein Secretory Pathway
62 Type 2 Protein Secretory Pathway
63 Type 3 Protein Secretory Pathway
64 Type 3 Protein Secretory Pathway_2
65 Type 4 Protein Secretory Pathway
66 Type 5& 6 Protein Secretory Pathway
67 Gram Positive Bacteria
68 Secretions & Biotechnology
69 Benefits to clone in Eukaryotes
70 Post translational modification of Proteins
71 Post translational modification of Proteins_2
72 Types of Eukaryotic Expression System
73 Saccharomyces cerevisae
74 Transofrmation in Yeast
75 Yeast Vector 1
76 Yeast Vector 2
77 Yeast Vector 3
78 Markers in Yeast
79 Promoters in Yeast
80 Pichia pastoris
81 Inclusion Bodies
82 Baculovirus-Insect Expression System
83 Baculovirus-Insect Expression System_2
84 Biomimetics
85 Biomimetics_2
86 Mammalian Cell Expression
87 Vectors for Mammalian Cell Expression
88 Vectors for Mammalian Cell Expression_2
89 Enhancing the Productivity
90 Enhancing the Productivity_2
91 Genome Editing Technologies
92 CRISPR CAS9
93 CRISPR CAS9_2
94 Pharmaceutical Biotechnology
95 Pharmaceutical Biotechnology Market
96 Hormones
97 Receptors and Drugable Proteins
98 Insuline the Hormone
99 Diabetes Mellitus
100 Insuline Receptor
101 Type 2 Diabetes
102 Insulin Molecule
103 Drawbacks of Animal Insulin
104 Genetically Engineered Insulin Production
105 Genetically Engineered Insulin Production_2
106 Insulin Analogs
107 Insulin Analogs_2
108 Glucagon
109 Human Growth Hormone
110 Human growth hormone the molecule
111 Therapeutic uses of growth harmone
112 Fertility Hormones
113 Male Reproductive System
114 Female Reproductive System
115 Female Reproductive System-2
116 Follicle Stimulating Hormone
117 Applications of Gonadotrophins
118 Vaccines a historical perspective 1
119 Vaccines a historical perspective 2
120 Traditional Vaccine preparation 1
121 Traditional Vaccine preparation 2
122 Recombinant vaccines_1
123 Recombinant vaccines_2
124 Recombinant vaccines_3
125 Peptide vaccines
126 Medical Implants
127 Biosensors
128 Drug Development Process
129 Point of care diagnostics
130 Point of care diagnostics 2
131 Point of care diagnostics 3
132 Theranostics & Pay for performance
133 Low Cost Diagnostics
134 Lateral Flow Immunoassay
135 The Last Word