Course Overview
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Course Synopsis
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This course of biochemistry is a very fundamental course and essential for all life sciences discipline. General biochemistry is a introductory course of molecules of life, e.g carbohydrates, lipids, proteins, DNA, bio-processes, bio catalysts, cellular respiration: oxidative phosphorylation and energy metabolism in general.
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Course Learning Outcomes
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General Biochemistry
- Learn about the structure, functions and properties of proteins, lipids, carbohydrates and nucleic acids.
- Demonstrate a comparative study of plant animal and microbial biochemistry
- Understand about the enzyme kinetics and enzyme mechanisms
- Develop problem solving skills and analytical thinking skills
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Course Calendar
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Week 01
1
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Introduction to Carbohydrates
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2
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Carbohydrates-Disaccharides
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3
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Carbohydrates-Polysaccharides
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4
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Carbohydrates-Isomerism
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5
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Carbohydrates-Chiral centers,double bonds
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6
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Carbohydrates-D and L isomerism
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7
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Carbohydrates-Enantiomers, Optical activity
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8
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Carbohydrates-Optical activity (Conti....)
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9
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Carbohydrates-Cyclic (ring) structures
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10
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Carbohydrates-Cyclic (ring) structres (Conti...), anomers
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11
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Carbohydrates-ring structure of monosaccharides
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12
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Carbohydrates: Epimers, Trioses, Tetroses, Pentoses
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13
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Carbohydrates: D-Galactose, D-Fructose, Properties of monosaccharides
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14
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Carbohydrates: Properties of monosaccharides
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15
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Carbohydrates: Properties of monosaccharides (Conti....)
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16
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Carbohydrates: Properties of monosaccharides 1 (Conti....)
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Week 02
17
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Carbohydrates: Properties of monosaccharides 2 (Conti....)
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18
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Carbohydrates: Properties of monosaccharides 3 (Conti....)
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19
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Carbohydrates: Properties of monosaccharides 4 (Conti....)
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20
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Carbohydrates: Properties of monosaccharides 5 (Conti....)
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21
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Carbohydrates: Properties of monosaccharides 6
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23
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Disacharrides (Conti....)
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24
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Disaccharides 1 (Conti....)
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28
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Properties of Proteins
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29
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Composition of Proteins
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30
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Composition of Proteins (Conti....)
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31
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Composition of Proteins 1 (Continued)
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32
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Composition of Proteins 2 (Conti....)
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33
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Composition of Proteins 3 (Conti....)
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34
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Conventions used to identify the carbons in amino acids
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Week 03
35
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Acidic and basic properties of amino acids
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36
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Acidic and Basic properties of amino acids (Conti...)
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37
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Acidic and Basic properties of amino acids 1 (Conti….)
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38
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Acidic and Basic properties of amino acids 2 (Conti….)
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39
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Acidic and Basic properties of amino acids 3 (Conti….)
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40
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Acidic and Basic properties of amino acids 4 (Conti….)
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41
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Acidic and Basic properties of amino acids 5 (Conti….)
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42
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Acidic and Basic properties of amino acids 6 (Conti….)
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43
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Abbreviations and symbols of amino acids
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44
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Classification of amino acids: A. Aliphatic R groups
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45
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Classification of amino acids: A. Aliphatic R groups (Conti...)
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46
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Classification of amino acids: Aromatic amino acids
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47
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Classification of amino acids: Aliphatic, Polar Uncharged R groups
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48
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Classification of amino acids: Positively charged (Basic R groups)
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49
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Classification of amino acids: Negatively charged (Acidic) R groups
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50
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Classification of amino acids: Glucogenic or ketogenic
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51
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Classification of proteins
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Week 04
52
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Functional classification of proteins
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54
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Structural Hierarchy of Proteins
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56
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The Secondary structure
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57
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The Secondary structure (Conti...)
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58
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The Secondary structure 1 (Conti...)
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59
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The Secondary structure 2 (conti...)
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60
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The Secondary Structure 3 (conti...)
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61
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The Secondary Structure 4 (conti...)
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62
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The Tertiary Structure
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63
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The Tertiary structure (conti....)
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64
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The Quaternary Structure
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Week 05
65
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The Quaternary Structure (Conti...)
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67
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Protein folding (Conti...)
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68
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Protein folding 1 (conti...)
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69
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Protein folding 2 (conti...)
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70
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Protein folding 3 (conti...)
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71
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Protein folding 4 (conti...)
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74
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Protein denaturation (conti...)
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75
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Reversible binding of a protein
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76
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Reversible binding of a protein (conti...)
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77
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Reversible binding of a protein 1 (conti...)
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78
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Reversible binding of a protein 2 (conti...)
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79
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Reversible binding of a protein 3 (conti...)
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80
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Reversible binding of a protein 4 (conti..)
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Week 06
81
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Reversible binding of a protein 5 (conti..)
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82
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Reversible binding of a protein 6 (Conti....)
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83
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Reversible binding of a protein 7 (Conti....)
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84
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Reversible binding of a protein 8 (Conti....)
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85
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Reversible binding of a protein 9 (Conti....)
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86
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Reversible binding of a protein 10 (Conti....)
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87
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Reversible binding of a protein 11 (Conti....)
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88
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Reversible binding of a protein 12 (Conti....)
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89
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Reversible binding of a protein 13 (Conti....)
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90
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Reversible binding of a protein 14 (Conti....)
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91
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Reversible binding of a protein 15 (Conti....)
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92
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Reversible binding of a protein 16 (Conti....)
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93
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Reversible binding of a protein 17 (Conti....)
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94
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Reversible binding of a protein 18 (Conti....)
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95
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Reversible binding of a protein 19 (Conti....)
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96
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Reversible binding of a protein 20 (Conti....)
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Week 07
97
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Reversible binding of a protein 21 (Conti....)
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98
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Reversible binding of a protein 22 (Conti....)
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99
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Reversible binding of a protein 23 (Conti....)
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100
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Reversible binding of a protein 24
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102
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Lipid Chemistry: Classification of lipids
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103
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Lipid Chemistry: Fatty Acids
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104
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Lipid Chemistry: Classification Of Fatty Acids
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105
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Lipid Chemistry: Nomenclature of Fatty Acids
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106
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Lipid Chemistry: Nomenclature of Fatty Acids (Conti....)
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107
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Lipid Chemistry: Physical and Chemical Properties of Fatty Acids
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108
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Lipid Chemistry: Physical and Chemical Properties of Fatty Acids (Conti....)
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109
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Lipid Chemistry: Physical and Chemical Properties of Fatty Acids 1(Conti....)
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110
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Lipid Chemistry: Physical and Chemical Properties of Fatty Acids 2 (Conti....)
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111
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Lipid CHemistry: Special Reactions of Unsaturated Fatty Acids
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112
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Lipid Chemistry: Polyunsaturated Fatty Acids Of Biological Importance
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Week 08
113
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Lipid Chemistry: Polyunsaturated Fatty Acids Of Biological Importance (Conti....)
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114
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Polyunsaturated Fatty Acids of Biological Importance
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115
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Polyunsaturated Fatty Acids Of Biological Importance Contd.
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116
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Unsaturated Fatty Acids of Physiologic and Nutritional Significance
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117
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Lipid Chemistry-Other Common Fatty Acids
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118
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Lipid Chemistry-Glycerol and Sphingosine
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119
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Lipid Chemistry: Sphingosine
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120
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Lipid Chemistry-Properties of Glycerol
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121
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Lipid Chemistry-Simple lipids
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122
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Lipid Chemistry-Triacylglycerols
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123
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Lipid Chemistry-Triacylglycerols (TAGs) Cont.
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124
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Lipid Chemistry-Properties of TAGs
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125
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Lipid Chemistry-Chemical Properties of TAGs
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126
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Lipid Chemistry-Chemical Properties of TAGs Contd
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127
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Lipid Chemistry-Chemical Properties of TAGs Contd.
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128
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Lipid Chemistry-Chemical Properties of TAGs Cont.
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Week 09
129
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Lipid Chemistry-Waxes
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130
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Lipid Chemistry-True Waxes
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131
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Lipid Chemistry-Lipids and Nutrition
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132
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Lipid Chemistry-Lipoproteins
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133
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Lipid Chemistry-Lipoproteins Contd
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134
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Lipid Chemistry-Lipoproteins Cont.
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136
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Lipid Chemistry-Role of Dietary Lipids
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137
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Lipid Chemistry-Role of Dietary Lipids Contd
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Week 10
138
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Lipid Chemistry-Structure of Phospholopids
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139
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Lipid Chemistry-Glycerophosholopids
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140
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Lipid Chemistry-Phosphotidylcholines
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141
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Lipid Chemistry-Phosphotidyl Ehanol Amine
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142
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Lipid Chemistry-Phosphotidylinositol
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143
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Lipid Chemistry-Ether Lipids
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144
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Lipid Chemistry-Sphingolipids
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145
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Lipid Chemistry-Glycosphingolipids
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146
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Lipid Chemistry-Glycosphingolipids Contd
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147
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Lipid Chemistry-ABO Blood Groups and Glycosphingolipids
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148
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Lipid Chemistry-Glycerophospholipids
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149
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Lipid Chemistry-Steroids and Cholesterol
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150
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Lipid Chemistry-Bile Acids & Bile Salts
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151
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Lipid Chemistry-Eicosanoids
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152
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Lipid Chemistry- Cyclooxygenase Pathway
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153
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Lipid Chemistry-Cyclooxgenase Pathway (Contd.)
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Week 11
154
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Lipid Chemistry-Lipoxygenase Pathway
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155
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Lipid Chemistry-Lipoxygenase Pathway (Contd)
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156
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Lipid Chemistry-Lipoxygenase Pathway (Contd.)
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157
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Lipid Chemistry-Lipoxygenase Pathway (Cont)
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158
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Nucleotides and Nucleic Acids
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159
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Nucleotides and Nucleic Acids- Biomedical importance of nucleotides
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160
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Nucleotides and Nucleic Acids- Biomedical importance of nucleotides (Contd)
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161
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Nucleotides and Nucleic Acids-Composition of Nucleotides
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162
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Nucleotides and Nucleic Acids- Composition of Nucleotides (Contd.)
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163
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Nucleotides and Nucleic Acids- Composition of Nucleotides (Cont.)
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164
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Nucleotides and Nucleic Acids- Composition of Nucleotides (Contd)
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165
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Nucleotides and Nucleic Acids- Properties of Nitrogenous Bases
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166
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Nucleotides and Nucleic Acids- Properties of Nitrogenous Bases (Contd)
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167
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Nucleotides and Nucleic Acids- N-glycosidic bond
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168
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Nucleotides and Nucleic Acids-Numbering of Carbon and Nitrogen Atoms
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169
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Nucleotides and Nucleic Acids- Phosphodiester Bond
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170
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Nucleotides and Nucleic Acids-Cyclic Nucleotides
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Week 12
171
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Nucleotides and Nucleic Acids-DNA
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172
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Nucleotides and Nucleic Acids-DNA Interactions
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173
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Nucleotides and Nucleic Acids-DNA Primary Structure
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174
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Nucleotides and Nucleic Acids-DNA Secondary Structure
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175
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Nucleotides and Nucleic Acids-DNA Tertiary Structure
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176
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Nucleotides and Nucleic Acids-DNA Properties
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177
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Nucleotides and Nucleic Acids-DNA Properties Contd
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179
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Nucleotides and Nucleic Acids-II
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180
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Nucleotides and Nucleic Acids-DNA Renaturation
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181
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Nucleotides and Nucleic Acids- RNA
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182
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Nucleotides and Nucleic Acids-Difference between RNA and DNA
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183
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Nucleotides and Nucleic Acids- RNA Structural Hierarchy
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184
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Nucleotides and Nucleic Acids- Secondary Structure of RNA
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185
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Nucleotides and Nucleic Acids- Messenger RNA
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186
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Nucleotides and Nucleic Acids- Transfer RNA
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Week 13
187
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Nucleotides and Nucleic Acids- Transfer RNA (continued..)
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188
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Nucleotides and Nucleic Acids- TRNA Continued
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189
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Nucleotides and Nucleic Acids- ribosomal RNA
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190
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Nucleotides and Nucleic Acids- small Nuclear RNA
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192
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Enzymes- classification
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193
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Enzymes- IUB classification (continued..)
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194
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Enzymes- IUB Classification (Continued...)
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196
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Enzymes- Mechanism of enzyme action
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197
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Enzymes- Mechanism of enzyme action (continued..)
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198
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Enzymes-Mechanism of action (continued...)
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199
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Enzymes-Mechanism of Action- Activation Energy (continued...)
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200
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Enzymes- induced fit hypothesis
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201
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Enzymes- co factors, coenzymes
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202
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Enzymes-Reaction rates and order
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Week 14
203
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Enzyme-Factor affecting enzyme activity
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204
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Enzymes-Factors (continued..)
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205
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Enzymes-Enzyme kinetics
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206
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Enzymes-Enzyme kinetics (continued..)
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207
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Enzymes-Enzyme kinetics Km (continued...)
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208
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Enzymes-Michaelis menten equation
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209
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Enzymes-Michaelis Menten equation (continued..)
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210
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Enzymes-Michaelis menten equation at low [S]
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211
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Enzymes-Michaelis Menten equation at high S
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212
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Enzymes-Order of reaction
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213
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Enzymes-Line Weaver Burke plot
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214
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Enzymes-Inhibition of Enzyme Activity
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215
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Enzymes-Competitive Inhibition
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216
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Enzymes-Competitive inhibition (continue...)
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217
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Enzymes-Non competitive inhibition
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218
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Enzymes-Non competitive inhibition (continued...)
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220
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Water PH and buffer systems ionization of water
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221
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Water PH and Buffer systems working examples
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222
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Water PH and buffer systems weak acids and bases
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223
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Water PH and buffer systems-working with pKa
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224
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Water PH and buffer systems HH equation
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225
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Water PH and buffer systems buffer solutions
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