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BIO502 : Genomics

Course Overview

Course Synopsis

This course of Genomics is divided into two basic areas: structural genomics, characterizing the physical nature of whole genomes; and functional genomics, characterizing the transcriptome (the entire range of transcripts produced by a given organism) and the proteome (the entire array of encoded proteins).

Course Learning Outcomes

Basic and General Genomics

  • Students who are pursuing this course of genomics will enable themselves to grab the concept of basic and general genomics, in which students learn about the structural genomics, characterizing the physical nature of whole genomes; and functional genomics, characterizing the transcriptome. Other potential topics in the curriculum include a proteome (the entire array of encoded proteins).

Course Calendar

1What is geneticsPPTN/A
2Sub discipilines of GeneticsPPTN/A
3Genetics TerminologiesPPTN/A
4Mendel s’ law of DominancePPTN/A
5Monohybrid Cross and Dihybrid CrossPPTN/A
6Mendel s’ law of SegregationsPPTN/A
7Mendel s’ law of Independent AssortmentPPTN/A
8Modern Genetics ConceptsPPTN/A
10Mendelian and Non-Mendelian InheritancePPTN/A
11Conclusions of Mendelian InheritancePPTN/A
12Exceptions to Mendelian InheritancePPTN/A
13Incomplete DominancePPTN/A
15Polygenic traitsPPTN/A
18Environmental EffectsPPTN/A
19Euchromatin and HeterochromatinPPTN/A
20Staining and Banding ChromosomesPPTN/A
22Chromatin and ChromosomesPPTN/A
23Higher Order Chromatin FoldingPPTN/A
26Prokaryotic ChromosomesPPTN/A
27Sex Chromosomes and Sex determinationPPTN/A
28Salient features of DNAPPTN/A
29Nucleotides – building blocks of DNAPPTN/A
30Conformations of DNAPPTN/A
31Chargaff Rule of Base RatioPPTN/A
32Cell CyclePPTN/A
33Summary - Mitosis and MeiosisPPTN/A
34Concept of Multiple AllelesPPTN/A
35Multiple Alleles - our blood groupPPTN/A
36Blood groups and TransfusionsPPTN/A
37Multiple alleles effect in rabbitsPPTN/A
38Correlation of Alleles and GenotypesPPTN/A
39Polygenic InheritancePPTN/A
40Examples of Polygenic inheritancePPTN/A
41What is EpistasisPPTN/A
Assignment No 1.
42Types of EpistasisPPTN/A
43What is EpigeneticsPPTN/A
44Epigenetic ModificationsPPTN/A
45Chromosomal AberrationsPPTN/A
46Karyotyping- international descriptionPPTN/A
47Defining Chromosome LocationPPTN/A
48Common Numerical AbnormalitiesPPTN/A
54Polyploidy and AneuploidyPPTN/A
55Structural AbnormalitiesPPTN/A
57Chromosomal DeletionsPPTN/A
58Chromosomal duplication      Current LessonPPTN/A
59Chromosomal InversionsPPTN/A
60Inheritance Patterns of Genetic DisordersPPTN/A
61Autosomal Recessive InheritancePPTN/A
62Autosomal Dominant InheritancePPTN/A
63X-linked recessive inheritancePPTN/A
64X-linked dominant inheritancePPTN/A
65Maternal inheritance of mt DNAPPTN/A
66Polymerases I and IIIPPTN/A
67Polymerases I and III (Conti...)PPTN/A
68RNA SplicingPPTN/A
69How splicing site is determinedPPTN/A
70Removal on IntronsPPTN/A
71The SpliceosomePPTN/A
72The Splicing PathwayPPTN/A
73Self-Splicing IntronsPPTN/A
74Group I IntronsPPTN/A
75Finding the Splice Sites CorrectlyPPTN/A
76Introduction to genomicsPPTN/A
77Functional GenomicsPPTN/A
78Structural genomicsPPTN/A
79Comparative genomicsPPTN/A
80Population GenomicsPPTN/A
82Genetics and GenomicsPPTN/A
83Genomics, Proteomics and metabolomicsPPTN/A
84Why sequence genomesPPTN/A
85Genome characterization-technique usedPPTN/A
86Genome analysis stepsPPTN/A
87Benefits of Genomes researchPPTN/A
88Genes and Sizes of GenomesPPTN/A
89Viral GenomesPPTN/A
90Bacterial genomesPPTN/A
91Yeast genomePPTN/A
92Mitochondrial genomePPTN/A
93Chloroplast genome (cpDNA)PPTN/A
94Eukaryotic genomesPPTN/A
95Genomes ComparisonPPTN/A
96Comparing distantly and closely related speciesPPTN/A
97Anatomy and organization of genomePPTN/A
Gene anatomyPPTN/A
Special Assignment (in lieu of Midterm Examination)
Prokaryotic gene and eukaryotic genePPTN/A
Types of eukaryotic DNAPPTN/A
Duplicated genes and Pseudo genesPPTN/A
Repetitive DNAPPTN/A
Movement of transposons and retrotransposonsPPTN/A
Transposons in Prokaryotes and EukaryotesPPTN/A
Long terminal repeatsPPTN/A
Genetic VariationsPPTN/A
Gene families and Gene clustersPPTN/A
Gene densitiesPPTN/A
Genome evolutionPPTN/A
Molecular Phylogenetic AnalysisPPTN/A
Genes tree and species treePPTN/A
Mitochondrial Genome EvolutionPPTN/A
Genome evolution – Nucleotide substitutionPPTN/A
Genome evolution CpG mutation ratePPTN/A
Genome evolution – IndelsPPTN/A
Genome evolution Gene conversionPPTN/A
Genome evolution-Gene DuplicationsPPTN/A
Genome Evolution Exons Shuffling and duplicationsPPTN/A
Genome evolution – Recombination hotspotsPPTN/A
Genome evolution double stranded break repairPPTN/A
Genome evolution chromosomal rearrangementsPPTN/A
Gene expression mechanismsPPTN/A
Gene expression and gene switchesPPTN/A
inducible and repressible sysytemsPPTN/A
Regulation of gene expression in prokaryortesPPTN/A
Quiz No 1.
Operon Model of prokaryotesPPTN/A
Eukaryotic gene expressionPPTN/A
Control of gene expression in EukaryotesPPTN/A
Cis acting elementsPPTN/A
Trans acting elementsPPTN/A
Gene expression and RNA interferencePPTN/A
Prokaryotic and Eukaryotic Expression differencePPTN/A
Genome mappingPPTN/A
Genetic mapping of the GenomesPPTN/A
Genetic MarkersPPTN/A
Characteristics of the genetic markersPPTN/A
DNA markersPPTN/A
Applications of Molecular markersPPTN/A
Physical mapping of the genomePPTN/A
Cytogenic mappingPPTN/A
FISH mappingPPTN/A
Restriction mapping of the genoomePPTN/A
Radiation hybrid mapping of the genomePPTN/A
Clone contig mapping of the genomePPTN/A
Generating Sequence of the genomesPPTN/A
Human Genome ProjectPPTN/A
Human Genome Project- Hierarchical Short Gun sequencing approachPPTN/A
Human Genome Project- Whole Genome Short Gun sequencing approachPPTN/A
Characteristics of our Genome part 1PPTN/A
Characteristics of our Genome part 2PPTN/A
Gene FunctionsPPTN/A
Genome Browsers UCSCPPTN/A
Genome Browsers ENSEMBLEPPTN/A
The hap map projectPPTN/A
the 1000 genomesPPTN/A
HGP ethical and legal issuesPPTN/A
HGPfuture challengesPPTN/A
Genome annotations Protein coding genesPPTN/A
genome annotations : transcription factorsPPTN/A
Genes predictions in prokaryotesPPTN/A
Gene Predictions in EukaryotesPPTN/A
Arabidopsis GenomePPTN/A
Mouse genomePPTN/A
Comparison between mouse and human genomePPTN/A
Proteomics Types and TechniquesPPTN/A
Characteristics of Human ProteomePPTN/A
Assignment No 2.
Mapping of disease genesPPTN/A
Type of linkage analysisPPTN/A
Genome wide association studiesPPTN/A
Association studies vs linkage studiesPPTN/A
Types of microarrayPPTN/A
Microarray FormatsPPTN/A
Microarray – ApplicationsPPTN/A
Types of RNA and RNomicsPPTN/A
Non coding DNAPPTN/A
Non coding RNAsPPTN/A
Biogenesis of miRNAPPTN/A
Functions of miRNAPPTN/A
Non coding RNA and X chromosome SilencingPPTN/A
RNA Induced Silencing ComplexPPTN/A
Dicer and DroshaPPTN/A
Design of siRNAPPTN/A
Applications of siRNAPPTN/A
Small ribozymes and riboswitchesPPTN/A
Pharmacogenetics and PharmacogenomicsPPTN/A
Pharmacogenomics principles and potentialsPPTN/A
Study of OmicsPPTN/A
Final Term Exams
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