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BIO734 : Advances in Cell Biology

Course Overview

Course Synopsis

This course will help post graduate students to understand the building blocks of life "The cells", how they made up of, cell constituents, cell interaction, cell processes, cell signaling and cells in system biology as a whole. Furthermore, it is best course for understanding molecules and units of life, biocatalysts, cell division/membranes, its origin and genetics in general. In the latter half of the course advanced topics are explained for better understanding of topics which includes cell junctions, Communicating/Gap Junctions, Plasmodesmata: Plant Gap Junctions, Cadherins, Cadherin link to actin, Cadherins & Development, Integrins, Integrin Cytoskeleton Interaction, GAG Organization, Filament Treadmilling, MAPs, IF Cross-linking, Actin Organization, Actin Organization 2, Severing Proteins, Molecular Motors, Force Generation, Kinesins & Dyneins, Intracellular Transport, Muscle Contraction, Anatomy of the Muscle Cell, Muscle Contraction Animation. After taking this course, students will be well familiar to the advances in cell biology but it will not be end of learning because there are many avenues to explore yet in this arena of knowledge.

Course Learning Outcomes

Advances in Cell Biology

  • After taking this course, students will enable themselves to understand the advanced topics of cell biology cum road map for further advanced courses in the same subject or other related arena of cell/molecular biology, genetics and bioinformatics. this advanced course will tune the students to meditate on the latest trends in cell biology, practical aspects that how a student think about the research topics. what is going on in the real world in this subject of great concern in the context of personalized medicine and other areas of great concern in todays world. As far as the different topics are concerns, students will learn Cell Scaffolds, GAG Organization, Cell-Surface Proteoglycans, Controlled Degradation of ECM, The Cytoskeleton Introduction, Cell origin, Cell evolution, Cell interactions, Cell mobility, Cell processes and Cell membranes.

Course Calendar

Introduction to Cell Biology1ppts
Composition of Matter2ppts
Molecules of Life3ppts
Ptoteins: Polymers of Amino Acids4ppts
Protein Structure5ppts
Protein Interaction6ppts
Carbohydrates: Sugar Polymers7ppts
Carbohydrates: Glycosidic linkages8ppts
Lipids: Nonpolar Hydrocarbons9ppts
Lipids: Saturated & Unsaturated10ppts
Nucleic Acids: DNA & RNA11ppts
RNA & DNA12ppts
Unit of Life13ppts
Journey into the Cell14ppts
Size Matters15ppts
The Nucleus16ppts
The Endoplasmic Reticulum18ppts
Golgi & Lysosomes19ppts
Motor Proteins21ppts
The Miracle Workers22ppts
Membrane Components24ppts
Assignment # 1
Recognition and Adhesion25ppts
Transport across membranes26ppts
Vesicle formation27ppts
Cell division28ppts
Cell Cycle29ppts
Transcription regulation37ppts
Transcription regulation in E.Coli38ppts
Transcription Regulation in E.Coli 239ppts
Transcription Regulation in Eukaryotes40ppts
Eukaryotic Transcription41ppts
RNA Processing42ppts
Cell signalling and prehistoric world43ppts
The Instructions and the Design44ppts
The Modes and Principles45ppts
The Modes and Principles II46ppts
The Modes and Principles III47ppts
Signalling in E.Coli48ppts
Assignment # 2
G protein linked receptor49ppts
Protein Kinases A50ppts
G proteins51ppts
G proteins vision52ppts
Cell signalling and Us53ppts
Cell signaling and memory54ppts
Enzyme linked receptors55ppts
Enzyme linked receptors 256ppts
Enzyme linked receptors 2 (Conti...)57ppts
RTK signalling gone wrong58ppts
PI3 Kinase59ppts
PKB apoptosis inhibition60ppts
JAK-STAT signaling61ppts
TGF-Beta receptor Family62ppts
Proteolysis Signaling Pathways63ppts
Immune system64ppts
Immune system 265ppts
Immune system 366ppts
The B-Cells68ppts
The B-Cells 269ppts
The Antibodies70ppts
Immunological memory71ppts
Acquired Immunological Tolerance72ppts
Antibody diversity73ppts
Class Switching74ppts
T-Cells and TCR75ppts
APCs activate T cells76ppts
Cytotoxic T cells78ppts
Helper T Cells79ppts
TH-1 and TH-280ppts
TH-2 B-Cell activation81ppts
Checks and Balances82ppts
Complement System83ppts
Complement System 284ppts
The Alternative Pathway85ppts
Neoplastic Transformation86ppts
Growth promoting oncogenes87ppts
Growth promoting oncogenes Cyclins and CDKs88ppts
Growth promoting oncogenes Cyclins and CDKs (Conti..)89ppts
DNA Repairing genes90ppts
Apoptosis Genes91ppts
Protein Sorting92ppts
Protein Sorting Mechanism93ppts
Nuclear Transport94ppts
Nuclear localization signals [NLSs] and transport95ppts
Nuclear Receptors96ppts
Special Assignment
The Ran Cycle97ppts
Control of import and export98ppts
Protein Transport into Mitochondria99ppts
The Translocators100ppts
ER Transport Introduction101ppts
ER Transport102ppts
Multipass Transmembrane Proteins104ppts
Vesicle Transport105ppts
COPI the Retrieval Process107ppts
Lysosomal Transport108ppts
Tissue Replacement110ppts
Organ repair via stem cell111ppts
Customized stem cells112ppts
Adult stem cells113ppts
Cytokines induced stem cell proliferation and differentiation114ppts
In-vitro organ/tissue fabrication115ppts
Introduction to the advance cell biology116ppts
Cell Junctions117ppts
Communicating/Gap Junctions118ppts
Plasmodesmata: Plant Gap Junctions119ppts
Occluding Junctions120ppts
The Anatomy of Occluding Junctions121ppts
Anchoring Junctions122ppts
Adherens Junctions123ppts
Cadherin link to actin126ppts
Cadherins & Development127ppts
A Plant’s Story128ppts
Transient Cell-Cell Adhesions129ppts
Selectins & cytoskeleton130ppts
Ca2+-independent Cell-Cell Adhesion131ppts
Assignment # 3
Integrin Diversity133ppts
Integrin Cytoskeleton Interaction134ppts
Anchor Proteins Introduction135ppts
Anchor Proteins Detailed View136ppts
Integrin regulation137ppts
Extracellular Matrix(ECM)139ppts
Glycosaminoglycan (GAG)140ppts
Hyaluronan (hyaluronic acid or hyaluronate)141ppts
Proteoglycans & Glycoproteins142ppts
More Than Scaffolds143ppts
GAG Organization144ppts
Cell-Surface Proteoglycans145ppts
ECM: Collagens146ppts
Non-Fibril Collagens147ppts
Collagen Secretion148ppts
Collagen Continued149ppts
Fibril Associated Collagen (FAC)150ppts
Cell Organize Collagen Fibrils151ppts
Fibronectin Forms154ppts
Basal Lamina (Basement Membrane)155ppts
Basal Lamina Additional Functions156ppts
ECM: Cell Shape, Survival & Proliferation157ppts
Controlled Degradation of ECM158ppts
The Cytoskeleton Introduction 1159ppts
The Cytoskeleton Introduction 2160ppts
The Cytoskeleton Introduction 3161ppts
Thermal Stability162ppts
Cytoskeletal Polymer Nucleation163ppts
Polar Filaments 1164ppts
Polar Filaments 2165ppts
Growth Rates166ppts
Filament Treadmilling167ppts
Treadmilling Animation168ppts
Dynamic Instability169ppts
Dynamic Instability Animation170ppts
Tubulin & Actin Isoforms171ppts
Intermediate Filament172ppts
IF Diversity173ppts
IF Genes Mutations174ppts
Cytoskeletal Drugs175ppts
Actin Filament Nucleation178ppts
Actin Filament Elongation179ppts
Tropomyosin & Cofilin180ppts
IF Cross-linking184ppts
Actin Organization185ppts
Actin Organization 2186ppts
Severing Proteins187ppts
Molecular Motors188ppts
Force Generation189ppts
Kinesins & Dyneins190ppts
Intracellular Transport191ppts
Muscle Contraction192ppts
Anatomy of the Muscle Cell193ppts
Muscle Contraction Animation194ppts
Final Term Exam
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